Ha batho ba tsofala, ho theoha ha tšebetso ea boko ho bonahala haholoanyane. Har'a batho ba lilemo li 20-59, boholo bo qala ho hlokomela ho theoha ha mosebetsi oa kelello ha ba lahleheloa ke mohopolo kapa ho lebala. Bakeng sa batho ba lilemo li 50-59, ho phethahala ha molumo oa kelello hangata ho tla ha ba qala ho e-ba le khefu e hlokomeloang mohopolong.
Ha ba ntse ba hlahloba mekhoa ea ho ntlafatsa tšebetso ea boko, lilemo tse fapaneng tsa lilemo li shebisisa likarolo tse fapaneng. Batho ba lilemo li 20-29 ba tloaetse ho tsepamisa ho ntlafatsa boroko ho matlafatsa ts'ebetso ea boko ba bokoang (ba lilemo li 44.5%). Bakeng sa ba lilemo tse 40-59, ba ntlafalitse tlhokomelo ea ho ntlafatsa tšebetso ea boko (lilemo tse 40-59: 43.4%).
Lisebelisoa tse tsebahalang 'marakeng oa bophelo ba Japane oa boko oa boko
Tumellanong le mokhoa oa lefatše oa ho phela bophelo bo botle ba bophelo, 'maraka oa lijo oa Japane o tiisa ka ho khetheha mathata a bophelo bo botle, ka bophelo ba boko ba boko. Ka la 11 Tšitoe 2024, Japane e ne e ngolisitse lijo tse 1,012 tse sebetsang (ho latela data ea semmuso), eo ba 79 e neng e amana le bophelo ba boko. Har'a tsena, GABA e ne e le motsoako o sebelisitsoeng khafetsa, o lateloa kelutein/Zeaxanthin, ginkgo Leaf e tsoang (flavonooids, li-terene),Dha, Biridobacterium McC1274, Portulaca Oleracea Saponis, PakiTitazeline.PQQ, Ergofioneine.
1. GABA
Gaba (γ-Aminobutyric acid) ke acino e seng acino o fumanoeng ka motsamaisi le basebetsi mmoho le bona. Ka 1950, Roberts et ea 1949. Ka 1950, Roberts et ea 1949. O ile a supa GABA in likepe tsa Mammanatia, a thehile ka tšubung e sa lefelloeng ea glutamate kapa mabe a eona, actalyzylase.
GABA ke neurotransmitter ea tšoantšiso e fumanoeng haholo tsamaisong ea methapo ea mali. Ts'ebetso ea eona ea mantlha ke ho fokotsa ho beleha ha batho ba sa rateheng ka ho thibela phetisetso ea lipontšo tsa haufinyane. Bokong, teka-tekano lipakeng tsa li-neurotrakisong e hlophisitsoeng ke Giba le Neurochings
Boithuto bo bontša hore Gaba a ka hlorisa liphetoho tse ntle ho matlafatsa 'me a ntlafatsa mohopolo le mesebetsi ea kelello. Lithuto tsa liphoofolo li fana ka maikutlo a hore Gica e ntlafatsa memori ea nako e telele litoeba ka ho fokotseha ha lisele tsa lisente tsa Neuroendocrine tsa cc-12. Mehleng ea Clinical, Gaba o bontšoa ho eketsa mohopolo oa bokoko-reicuraphicm.
Ntle le moo, Gaba o na le litlamorao tse ntle tsa ho sithabe maikutlo, khatello ea maikutlo, mokhathala le boroko. Patlisiso e bonts'a hore motsoako oa Gaba le ho eketsa nako ea boroko, 'me u hlakoloe ke polelo ea Glun1 Reckin.
2. Lutein / zeaxanthin
Luteinke caroten ea oksijene e entsoe ka masala a robeli a polyene e nang le litla-morao tse peli, tse monyang ka li-waveleth tse ikhethang, li fang thepa e ikhethang ea mebala.ZeaxanthinNa moeta-pele oa Lutein, ea fapaneng maemong a kamano e habeli ho reng.
Lutein le Zeaxanthinke mebala ea mantlha ea ho retina. Litelin e fumanoa haholo-holo bohareng ba thepa ea peripheral, ha Zexanthin o tsepamisitsoe ke Macula e bohareng. Litholoana tsa ho sireletsaLutein le ZeaxanthinEtsoe mahlo a kenyelletsa pono e ntlafalitsoeng, ho thibela batho ba amanang le boholo ba AMD), MABAKA, Glaucoma le ho thibela ho rethela ho hang.
Ka 2017, bafuputsi ba tsoang Univesithing ea Georgia ba fumane seoLutein le ZeaxanthinHo ama bophelo bo botle ba boko ho batho ba baholo. Thuto e bontšitse hore barupeluoa ba nang le maemo a phahameng aLutein le ZeaxanthinHo bonts'a tšebetso ea kelello e tlase ha u etsa mesebetsi e hopolang mantsoe, e fana ka maikutlo a ts'ebetso e phahameng haholo ea haufinyane.
Ho feta moo, ho ile ha tlalehoa hore Lundax 2020, tlatsetso ea Lutele, e leng seprothekeng ea Bdnf, le phapang ea li-neuron, le tse amanang le Ho ithuta ho ithutoang, mohopolo le ts'ebetso ea kelello.
(Manonyeletso a sebopeho sa lutein le zeaxanthin)
3. Ginkgo Leaf Extract (FlavonOids, li-terene)
Ginkgo Biloba, e leng feela mefuta e phethahetseng ea lelapa la Ginkygo, hangata e bitsoa "mesira e mengata ea khale." Makhasi a eona le lipeo li tloaetse ho sebelisoa lipatlisiso tsa meriana mme ke e 'ngoe ea meriana e sebelisoang haholo ka ho fetisisa lefatšeng ka bophara. Metsoako e sebetsang ho Ginkgo Leaf Exnxct ke lintho tse ling tse nang le thepa e nang le thepa e tšoanang, ho fokotsa khatello ea mahlo
Likhakanyo tsa Mokhatlo oa Lefatše oa Bophelo mabapi le Merusu ea Meetso e supa e tšoanangginkgoLekhasi le letšo le lokela ho ba le li-glycosoid tse 22-27% Glycosoid le 5-7% li-tepenode, ka litaba tsa ginkgolic tse ka tlase ho 5 mg / kg. Japane, mokhatlo oa lijo o phepo ea phepo ea bophelo bo botle o behile litekanyetso tsa boleng bakeng sa ginkgo lefōljo tse tlase tsa ginkgosi ea bonyane tse 24%, ka acid ea ginkgolic e ne e lula e le ka tlase ho 5 ppm. Ho khothalletsoa ho khothalletsoa letsatsi le letsatsi ho feta batho ba baholo ho pakeng tsa 60 le 240 mg.
Boithuto bo bontšitse hore tšebeliso ea letsatsi le nako e tšoanang ea ginkgo extract, e bapisoang le ho nepahala ha kelello, ho kenyelletsa ho nepahala ha mohopolo le bokhoni ba kahlolo. Ho feta moo, ho tlalehiloe hore Gykhko Explrect e tlalehiloe ho ntlafatsa phallo ea mali le tšebetso.
4. Dha
Dha. E tletse lijong tsa leoatleng le lihlahisoa tsa bona haholo, haholohla-holo lihlapi tse mafura, tse fanang ka ligrama tsa DHA ka ligrama tse 100. Lijo tse thehiloeng liphoofolo tse kang mahe le nama li na le chelete e nyane ea dha. Ho feta moo, lebese la masisa-pelo la batho le lebese le leng le anyesang le lona le na le Dha. Patlisiso e mabapi le lithuto tse fetang 2,400 tse fetang tse 65 li fumana hore boima ba Dha ka lebese la matsoele ke 1,06% ho 1,4% ho isa ho lebese la sefuba.
Dha o amahanngoa le kholo ea boko, ts'ebetso le mafu. Patlisiso e batsi e bonts'a seoDhaU ka matlafatsa neurotrachin, kholo ea neilecal, polasetiki ea dynaptic, le neurotransmitter tokollo. Tlhahlobo ea liteko tse 15 tseo ho sa reroang ka mokhoa o ikhethileng e bontšitse hore karolo ea letsatsi le letsatsi ea 580 mg ea ho ntlafatsa memori ea sehlooho e fetisisang haholo le ba nang le khatello ea maikutlo.
Mechine ea DHA ea tšebetso e kenyelletsa: 1) Ho khutlisetsa tekanyo ea N-3 / N-6 PUA; 2) Ho thibela neuronfem e amanang le lilemo tse amanang le M1 Microglistal cell overactivation; 3) Ho hatella Phenocyte Phenotype Phenotype ka ho theola matšoao a A1 e kang C3 le S100b; 4) Ho thibela tsela ea ho supa / P75 ea ho supa ntle le tsela e sa tsoaneng ea boko le 5) ho khothaletsa ho pholoha ha sauroal ka ho eketsa maikutlo a phosphamithallies, e ratang propein kinase b (akt) tranfacation le ts'ebetso.
5. Bifidobacterium McC1274
Ho bontšitsoe ka hlooho, hangata ho bitsoa "bo bokong ba bobeli," ho bontšitsoe e le ho ba le bokhachane ba bohlokoa le boko. Leqheka leo, e le setho sa mokhatlo oa boipuso, o ka sebetsa ntle le ho fana ka tataiso ka kotloloho ntle le thuto ea kelello. Leha ho le joalo, khokahano lipakeng tsa gut le boko e hlokomeloa ka mokhoa oa letsoalo, lipontšo, le li-cytokines, li theha "li-apos tse bokoang ke li-gut-gut-pout-boko."
Patlisiso e senotse hore baktheria e bapala karolo ea protheine ea β-Amyloid lefu la thuto ea bolumeli. Ha ho bapisoa le taolo e phetseng hantle, bakuli ba Alzheimer ba fokotsehile ka li-vicrobisota tse ngata, ka ho fokotseha ha bongata ba bilidobacterium.
Lithutong tsa batho tsa ho kenella ho batho ba nang le tsitsipano e bonolo (MCA) Litlama libakeng tse kang mohopolo o makatsang oa hanghang, bokhoni ba pono, ts'ebetso e thata le mohopolo o liehang o ile oa ntlafala haholo.
Nako ea poso: Jan-08-2025